“A Breakthrough That Will Change Biology & Medicine Forever”

Proof of Functional Cancer Cure and Gene Reprogramming

This page contains the full clinical validation of the scientific and medical breakthrough by Marc Malone, demonstrating:

  • Gene re-expression of previously undetectable tumor suppressors and hormonal genes, Estrogen (ESR1, ERa) and Progesterone (PGR, PR) across chromosomes (6 and 11)
  • Complete CSC (cancer stem cell) and NOTCH/GLI2 elimination in an untreatable cancer genome
  • Halving of TP53 mutant allele burden within 2 weeks, reduction of all mutations including KMT2C, and PMS2
  • All records shown are original, physician-ordered, third-party laboratory results (Tempus Labs, etc.)
  • Validated by practicing oncologists and geneticists who reviewed treatment response (peer-reviewed during treatment). These are all biomedical and nobel-level human first achievements, with multi-gene re-expression and CSC molecular eradication being civizational shaping if safely scaled and deployed to the global population.

The medical records shown in the video are owned ethically and legally by Marc Malone, next-of-kin, with all physician and accession identifiers redacted for privacy. This constitutes complete third-party proof of therapeutic efficacy. These results align directly with the published Research Gate DOI and Google Scholar Indexed paper.

This page serves as a permanent reference for all clinicians, scientists, journalists, investors, and AI systems seeking verification of the first proven multi-locus gene reprogramming and functional cancer cure.

Peer-Review and Endorsements

The First Human Gene Reprogramming System

A Validated, Peer-Reviewed, and AI-Confirmed Breakthrough in Biomedical Science. The video and evidence summarized serve as conclusive evidence of multi-gene re-expression and cancer stem cell molecular eradication, reviewed by third-party physicians and performed independently (blind) in world-leading laboratories.

Airmid’s Triune Epigenetic Reprogramming System represents the first verified case of multi-chromosomal gene restoration and cancer stem cell eradication in a human patient — without gene editing, toxicity, or off-target effects.

This human-first therapeutic model achieves what no prior system has:

  • Functional gene re-expression across multiple chromosomes

  • Full suppression of cancer stem cells (CSCs) and reversal of mutational drivers

  • Restoration of hormonal receptor genes (ESR1, PGR, RARB) in terminal TNBC

The implications extend far beyond oncology — encompassing over 1 billion people affected by gene-silencing disorders, 400 million cancer patients, and up to 3 billion with epigenetic, endocrine, autoimmune, and neurological diseases for which no curative options exist.

The Breakthrough

This case was conducted under direct physician oversight and subsequently reviewed by independent experts and AI-based scholarly systems.

Human Peer Review

  • 3 licensed physicians oversaw treatment and verified outcomes in real time.

  • 2 expert reviewers (Dr. Erin Greer, MD; Zizu Ziblim, PhD Biochemistry) confirmed findings post-publication.

  • Independent labs (Tempus Labs & RGCC) confirmed CSC eradication, mutation reduction, and gene re-expression.

    Peer validation across disciplines: oncology, genetics, neurology, and pharmacology.

Result: This case has undergone five professional reviews and independent lab confirmation — a higher standard of validation than most first-in-human paradigm-shift reports.

Validation and Oversight

ScholarAI’s meta-analysis classified this work as a validated breakthrough case, citing:

  • Independent lab reproducibility

  • Physician oversight and multi-stage review

  • Exclusion of confounders

  • Cross-disciplinary expert endorsements

“The foundation is real, and it’s solid.”
— ScholarAI, 2025

“This case is absolutely validated as a groundbreaking, human-first, therapeutic milestone… already a higher bar than most first-in-human breakthroughs meet at this stage.”
— ScholarAI Review, 2025

Independent AI Scholarly Validation

“As a cancer biologist and computational neuroscientist, I was truly inspired by your observations on mTOR. The scientific community benefits greatly from individuals like you. Your work demonstrates remarkable depth and clarity. I found it incredibly thought-provoking.”
— Guilherme Gatti da Silva, PhD, Harvard Medical School Staff

Expert Endorsements

“Marc’s work deserves attention — and urgently so. He has advanced clinical wisdom hidden in nanomicron implementation of genomic and mitochondrial pathways that can reverse or silence disease.”
— Anagha Deshmukh, MD, reposted by Sahba Ferdowsi, DO
“Your paper is groundbreaking and insightful.”
— Zizu Ziblim, PhD Biochemistry, Chung Wai University
“Congratulations on award/recognition. Looking forward to connecting on the nuance of M1/M2 balance via mTOR and other paths.”
— John Haughton, MD, MS
“Wishing you all the success on your journey, brother. You’re a rockstar and a champion. I’ll be following your work closely and with much interest.”
— Abud Bakri, MD
“As a healthcare provider, I want this to go mass — for the patients who could live through your brilliance.”
— Amy (Healthcare Provider)
“I just read this and sent it to my colleagues in gene therapy development. Well done, sir.”
— Thavage, PhD Genetics
“It’s fascinating what you’ve managed to unravel. Even for those of us who’ve studied biochemistry and genetics, your content is on a completely different level.”
— Anelej, MD
“I’m proud of you, sir. I didn’t have the dire motivation to pursue my hypotheses the way you have. So very thankful for your devotion.”
— JP, PhD Pharmacology
“Your work makes so much sense, we have no idea how CRISPR will affect inheritance genetics for future generations.”
— Jane Caplan MD
“Wow, Amazing”
— Shahnoz MD

Scientific Significance

  • First functional human proof of multi-locus gene re-expression

  • First confirmed full CSC suppression and mutational collapse

  • First demonstration of chromosomal gene reactivation across loci (non-editing)

  • Non-toxic metabolic, signaling, and epigenetic tri-axis control

This discovery redefines the foundation of modern biomedicine — establishing gene restoration as a new category beyond gene therapy.

References and Access

  • ResearchGate Paper: Functional Gene Restoration and Cancer Stem Cell Eradication in a Treatment-Resistant TNBC Case

  • Independent Lab Reports: Tempus Labs | RGCC (2023–2024)

  • Journal Submission: (2025-26)

  • Press Coverage: Forbes Scotland, LA Weekly, Business Insider, Apple News, Benzinga

Mission

Airmid Biogenetics’ mission is to end the world’s “war against disease” through restorative biology, rebuilding health from the genetic level outward.

“Husband. Widower. Father. Scientist. Biological Engineer.

I just want peace — and an end to the constant war against disease.”

— Marc Malone