I Became the First Human Gene-Reprogrammer to Save my Late Wife, now, to Save my Son.
Marc Malone: Widowed-Father, Self-Taught Scientist.
From Desperation to Discovery: How Love, Loss, and a Breakthrough Could Save a Billion Lives
My name is Marc. I’m a Widowed-father of 3 children who lost their mother. I’m not a professor. I don’t wear a lab coat. I had some scientific experience, but none in a deadly disease field. But I may have just opened up a safe and effective way to reprogram the human genome — and it all began with a fight to save my wife’s life.
She was diagnosed with one of the deadliest forms of cancer: triple-negative breast cancer (TNBC), and she was the peak lethal ultra-aggressive form of that type. The odds were against us. Every standard treatment failed. With odds of approximately <1% success surviving in her genomic profile. So I did what no one expected - I taught myself molecular biology, pharmacology, and genetics. I dove headfirst into the science, fueled by desperation, love, and the refusal to accept that there was no hope.
I created a new biological engineering system called the Triune Restoration Framework which targeted core genetic locks repressing genes, dysregulated metabolic state furthering disease, and intracellular molecular signal pathways looping it all together. This alone led to a tripled lifespan (3.8 months to 12 months), of which there’s no patient record of someone in her cancer profile to have lived to. Using a novel combination of FDA-approved compounds, nutraceuticals, and metabolic modulation to target these areas, I reprogrammed her gene expression reactivating silenced genes and hormone receptors (ESR1/PGR), and triggering a ~70% tumor reduction, metastatic lymph node removed - and with zero toxicity. No AI. No technology. No gene editing. No radiation. Just pure biochemical intervention. This is the first documented case of human epigenetic reprogramming restoring nonfunctional genes done without altering DNA. And the only multi-chromosome gene restoration ever recorded in a human being.
Towards the end of her life as she entered Hospice - I utilized a different system of reprogramming which released natural epigenetic enzyme modulation - in turn eradicating cancer stem cell molecular pathways. This is the first human record of full suppression of the drivers of all cancer (Notch, WNT, Hedgehog-GLI2 axis) which led to causal drop of all malignant mutations and tumor cells. While this miracle isn’t as big for the world as restored gene function across chromosomes, it would have been better for her specific disease - because it is the closest on record to a functional cancer cure in a human (which differs from ‘absolute cure’). I have mapped out an entirely original and fully reproducible formula of how to safely achieve this metabolic-genetic reprogramming so we can build upon it with further studies.
But our time ran out. Despite no conventional treatments regressing the disease, I regressed it twice, giving her baby birthdays she wouldn’t have had otherwise and surpassing all clinical baselines for her rare and ultra-lethal cancer. But. I had to learn oncology, genetics, molecular biology, and pharmacology as her tumors were growing an abominable 1cm a week (for contrast, the average breast cancer tumor grows 1cm in 17 months). She was dying right in front of me, and our 3 children–and I was widowed with them aged 3 and under when she died in my arms. 2 of my 3 children are severely Autistic, my youngest daughter Skye, and my oldest, Arran. So I was alone to raise 2 toddlers and a baby, 2 of which had serious disabilities.
Now, the mission continues - for my son.
He is, according to 287 million scientific records scanned, carrying the highest amount of functional mutations of any human ever (300+). He has profound Autism, cognitive disability, with mutations awaiting to emerge in neurodegeneration, and cancer, so many hundreds of cancer - all written into his code. He may not have long, and the probability of long term survival is even lower than Jillian’s was. Doctors see inevitability. I see possibility. Because what worked for her, with refinement, could work for him, and for many millions more. Genetic reprogramming is not a cancer cure, that's why, despite significant & positive treatment response Jillian died (because the functional cure came post-total organ tumor damage). Gene restoration is a cancer prevention mechanism. And no treatment could save my son, only prevention can.
This isn't just about one boy, or one family. Conservatively over 1 billion people live with conditions rooted in gene silencing and epigenetic dysfunction. From Cancer to Alzheimer’s, Infertility, Severe Autism to Autoimmunity; we’ve been treating symptoms while the genetic light switch stays off.
I am the only documented scientist in history to have a found a way to turn the genes back on. But we have to do so much more in research, dedication and safety evaluation before knowing for sure if this will save him, reverse Skye’s severe Autism as well, and help the Billion fellow humans in desperate need.
I am the only sole designer of a clinically proven (with significant disease reversal) cancer treatment that is also epigenetic in the world (doctor ‘co-authors’ provided clinical peer-review) and we published the first paper showing that global epigenetic reprogramming via biochemical-metabolic-genetic induction, not gene editing, is not only possible, but clinically effective and safe. Multiple notable third-party institutional labs confirmed the eradication of the cause of cancer growth (CSCs) and the multi-chromosomal gene re-expression of Estrogen and Progesterone. Several oncologists during treatment verified, as well as several dozen PhD’s and MD’s in relevant fields from Molecular Biology, Gene Therapy, Biochemistry and Pharmacokinetics - have open peer-reviewed the paper. It’s real. It’s human-tested. And it could change medicine and regenerative biology - forever.
I wasn’t supposed to be the one to do this. It was supposed to be an ivy-league scholar with a trust fund and perfect academic record; not a boy who grew up in poverty, in government housing, who lost his father at 7, his mother chronically sick at 10, lost his brother at 21, and then his wife and the mother of the home at 32. I formulated the only human genetic reprogramming treatment–and also cancer reducing treatment–in our basement at home in desperation. The rules of biology were cracked open by grief-stricken hands. I’d rather Jillian be alive than change the world. But watching my son struggle through his life and then die young is unacceptable. Watching millions upon millions of others suffer like us, is unacceptable. So I hope you will join me, support me, and help me, save my family from more disability & disease, more loss, and through Jillian and Arran’s pain we can help that Billion people as well. I have seen the genetic results of reprogramming in real-time, the terminal unstoppable disease reverse - so I know, impossible is not really impossible, and lacking hope is not a luxury I have. That many of us have.
I have to shoutout the doctors and nurses I worked with along the way, and the scientists who came before me. Without so much heavy research already being done in labs across the world, I wouldn’t have been able to do what I have done. I stand on their shoulders.
Airmid is only a name right now, I still work a 9-5 job, but the aspiration is we soon build it into bioscientific brilliance and finish the work that started with tragedy, so it ends with joy.
My late wife gave me the understanding and the proof that can lead to saving my son, and he can lead to saving so many others. Save the boy, save the world.
I appreciate you,
Marc.